MOTS-C 10MG

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What is MOTS-c?

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a powerful, naturally occurring peptide consisting of 16 amino acids. Discovered in 2015, it belongs to an exciting new class of signaling molecules called mitochondrial-derived peptides (MDPs). While most peptides are controlled by cellular DNA, MOTS-c is unique because it is encoded directly within the mitochondria—the powerhouse of the cell. In preclinical research, it acts as a cellular master-switch that activates key metabolic pathways to restore energy balance, combat cellular stress, and regulate full-body metabolic health.

Key Research Benefits & Mechanisms

  • Revitalises Metabolic Rate: Activates the AMPK pathway (the body's master metabolic sensor), which turns on fat-burning and forces cells to use energy more efficiently.
  • Supercharges Cellular Energy: Protects and enhances mitochondrial function, restoring youthful energy production levels at a foundational cellular level.
  • Combats Insulin Resistance: Triggers the expression of glucose transporter proteins (like GLUT4), helping cells clear sugar out of the bloodstream and into muscle tissue efficiently.
  • Mimics Exercise Benefits: Replicates many of the same physiological, cardiovascular, and metabolic advantages of intensive physical training within cellular models.
  • Promotes Longevity & Vitality: Targets cellular aging pathways, showing incredible potential in research aimed at reversing age-related metabolic decline and muscle loss.
  • Prevents Fat Accumulation: Restructures metabolic signaling to prioritize lipid (fat) breakdown while actively suppressing fat storage mechanisms.